Aicar (also known as AICAR or Acadesine) is a compound that activates AMP-activated protein kinase (AMPK), an enzyme involved in cellular energy homeostasis. It has been studied for potential benefits in metabolic regulation, endurance enhancement, and muscle performance.
AICAR Nasal Spray – Potential Uses & Considerations
Possible Applications:
Cognitive Enhancement: Some research suggests AMPK activation may support brain health and neuroprotection.
Metabolic Benefits: May aid in fat metabolism and insulin sensitivity.
Anti-Aging & Longevity: AMPK activation is linked to autophagy and cellular repair.
Nasal Spray Advantages:
Faster Absorption: Bypasses the digestive system, potentially increasing bioavailability.
Brain Targeting: Intranasal delivery may enhance direct effects on the central nervous system (CNS).
Current Status:
Not FDA-approved for any medical use.
Primarily used in research settings (e.g., metabolic studies, sports science).
Gray Market Availability: Some nootropic/supplement vendors sell it, but quality and safety are unverified.
Risks & Side Effects:
Lack of Human Safety Data: Long-term effects are unknown.
Possible Hypoglycemia: Since AICAR affects metabolism, it could lower blood sugar.
Muscle Fatigue: Some users report excessive tiredness after use.