AOD 9604 Nasal Spray

AOD-9604 Nasal Spray Delivery: Dosage, Effectiveness & Safety

AOD-9604 is a modified fragment of human growth hormone (hGH, amino acids 177-191) that has been studied for its potential fat-loss and metabolic effects. Unlike full hGH, it does not significantly affect insulin or growth pathways, making it an attractive option for targeted fat reduction.

Nasal spray delivery of AOD-9604 has gained popularity in anti-aging and weight-loss clinics, as well as in the peptide research community, due to its convenience and potential for systemic absorption.

1. How AOD-9604 Nasal Spray Works

• Mechanism: AOD-9604 stimulates lipolysis (fat breakdown) and inhibits lipogenesis (fat storage) by mimicking the effects of hGH on fat cells.

• Nasal Absorption: The nasal mucosa allows peptides to bypass the digestive system, potentially improving bioavailability compared to oral administration.

• Target Effects:

  • Reduces stubborn fat (especially abdominal)

  • May support metabolism without affecting blood sugar

  • Some reports of improved cartilage repair (anecdotal)

Example Nasal Spray Protocol:

• 300 mcg per spray (1 spray in each nostril = 600 mcg total)

• Taken once in the morning (fasted) or twice daily (morning & evening)

• Cycles typically last 8–12 weeks, followed by a break

2. Effectiveness of Nasal Spray vs. Injection

Conclusion:

• Nasal spray studies are more convenient but may require higher doses for similar effects.

• Injection remains the most reliable method for optimal results.

4. Safety & Side Effects

AOD-9604 is generally well-tolerated, but possible side effects include:

• Mild nasal irritation (if using spray)

• Headaches (rare)

• Increased hunger (some users report)

• No significant impact on blood sugar or IGF-1 (unlike full hGH)

Contraindications:

• Pregnancy or breastfeeding

• Active cancer (theoretical risk, though minimal evidence)