GHK-Cu (Copper-GHK) is a bioactive peptide known for its anti-aging, skin-repairing, and systemic healing properties. While traditionally used in injectable or topical for
ms, intranasal GHK-Cu is gaining interest for its potential cognitive and systemic benefits.
 
🔬 How GHK-Cu Works
Stimulates collagen & elastin → improves skin repair, reduces wrinkles.
Anti-inflammatory & antioxidant → protects against cellular damage.
Promotes wound healing & tissue regeneration (used in burns, scars).
May enhance cognitive function (via neuroprotection and angiogenesis).
Supports hair growth (by activating follicle stem cells).
 
👃 GHK-Cu Nasal Spray: Pros & Cons
 
✅ Potential Benefits of Intranasal Use
✔ Faster absorption than oral (bypasses digestion).
✔ Possible brain benefits (nasal route may enhance delivery to CNS).
✔ No injections needed (convenient for daily use).
✔ Systemic anti-aging effects (skin, joints, immune support).
 
❌ Possible Downsides
Lower bioavailability than subcutaneous injections.
Nasal irritation (some users report temporary stinging).
Limited human studies on nasal absorption (most research is on injections/topicals).
 
💉 GHK-Cu Nasal vs. Other Routes
Route
Bioavailability
Best For
Nasal Spray
Moderate (~30-50%?)
Convenience, cognitive support
Subcutaneous
High (~90%+)
Deep tissue healing, skin remodeling
Topical (Serum/Cream)
Localized (skin only)
Wrinkles, scars, hair growth
 
📊 Dosage & Usage Guide
For Nasal Spray (Research Guidelines)
Dose per spray: ~1-2 mg (varies by formulation).
Frequency: 1-2 sprays per day (morning/night).
Cycle: Can be used daily (no known receptor desensitization).
For Subcutaneous Injection (Research guidelines)
Typical dose: 1-2 mg/day (often mixed with BPC-157 for healing).
 
🧠 Potential Cognitive & Anti-Aging Effects
🔹 Neuroprotection (may help with brain fog, memory).
🔹 Reduces oxidative stress (linked to slower aging).
🔹 Improves skin texture (collagen boost).
🔹 Speeds up injury recovery (tendons, joints).
 
⚠️ Side Effects & Safety
Temporary nasal discomfort (burning sensation).
Metallic taste (common with copper peptides).
Very low systemic toxicity (studies show high safety profile).
💡 Final Verdict
✅ GHK-Cu nasal spray  research is promising for anti-aging, skin, and brain health, but injections/topicals may be more potent for deep tissue repair.